Before an item can be considered DME, it must meet all of the following requirements:

• It must be able to withstand repeated use.
• It must be primarily and customarily used to serve a medical purpose.
• It must be generally not useful to a person in the absence of an illness or injury.
• It must be appropriate for use in the home.

All E codes fall under the jurisdiction of the DME MAC unless otherwise noted.

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• E0464

  Pressure support ventilator with volume control mode, may include pressure control mode, used with non-invasive interface (e.g., mask)

• E0465

  Home ventilator, any type, used with invasive interface, (e.g., tracheostomy tube)

• E0466

  Home ventilator, any type, used with non-invasive interface, (e.g., mask, chest shell)

• E0467

  Home ventilator, multi-function respiratory device, also performs any or all of the additional functions of oxygen concentration, drug nebulization, aspiration, and cough stimulation, includes all accessories, components and supplies for all functions

• E0468

  Home ventilator, dual-function respiratory device, also performs additional function of cough stimulation, includes all accessories, components and supplies for all functions

• E0469

  Lung expansion airway clearance, continuous high frequency oscillation, and nebulization device

• E0470

  Respiratory assist device, bi-level pressure capability, without backup rate feature, used with noninvasive interface, e.g., nasal or facial mask (intermittent assist device with continuous positive airway pressure device)

• E0471

  Respiratory assist device, bi-level pressure capability, with back-up rate feature, used with noninvasive interface, e.g., nasal or facial mask (intermittent assist device with continuous positive airway pressure device)

• E0472

  Respiratory assist device, bi-level pressure capability, with backup rate feature, used with invasive interface, e.g., tracheostomy tube (intermittent assist device with continuous positive airway pressure device)

• E0480

  Percussor, electric or pneumatic, home model

• E0481

  Intrapulmonary percussive ventilation system and related accessories

• E0482

  Cough stimulating device, alternating positive and negative airway pressure

• E0483

  High frequency chest wall oscillation system, with full anterior and/or posterior thoracic region receiving simultaneous external oscillation, includes all accessories and supplies, each

• E0484

  Oscillatory positive expiratory pressure device, non-electric, any type, each

• E0485

  Oral device/appliance used to reduce upper airway collapsibility, adjustable or non-adjustable, prefabricated, includes fitting and adjustment

• E0486

  Oral device/appliance used to reduce upper airway collapsibility, adjustable or non-adjustable, custom fabricated, includes fitting and adjustment

• E0487

  Spirometer, electronic, includes all accessories

• E0490

  Power source and control electronics unit for oral device/appliance for neuromuscular electrical stimulation of the tongue muscle, controlled by hardware remote

• E0491

  Oral device/appliance for neuromuscular electrical stimulation of the tongue muscle, used in conjunction with the power source and control electronics unit, controlled by hardware remote, 90-day supply

• E0492

  Power source and control electronics unit for oral device/appliance for neuromuscular electrical stimulation of the tongue muscle, controlled by phone application

• E0493

  Oral device/appliance for neuromuscular electrical stimulation of the tongue muscle, used in conjunction with the power source and control electronics unit, controlled by phone application, 90-day supply

• E0500

  Ippb machine, all types, with built-in nebulization; manual or automatic valves; internal or external power source

• E0530

  Electronic positional obstructive sleep apnea treatment, with sensor, includes all components and accessories, any type

• E0550

  Humidifier, durable for extensive supplemental humidification during ippb treatments or oxygen delivery

• E0555

  Humidifier, durable, glass or autoclavable plastic bottle type, for use with regulator or flowmeter

• E0560

  Humidifier, durable for supplemental humidification during ippb treatment or oxygen delivery

• E0561

  Humidifier, non-heated, used with positive airway pressure device

• E0562

  Humidifier, heated, used with positive airway pressure device

• E0565

  Compressor, air power source for equipment which is not self-contained or cylinder driven

• E0570

  Nebulizer, with compressor

• E0572

  Aerosol compressor, adjustable pressure, light duty for intermittent use

• E0574

  Ultrasonic/electronic aerosol generator with small volume nebulizer

• E0575

  Nebulizer, ultrasonic, large volume

• E0580

  Nebulizer, durable, glass or autoclavable plastic, bottle type, for use with regulator or flowmeter

• E0585

  Nebulizer, with compressor and heater

• E0600

  Respiratory suction pump, home model, portable or stationary, electric

• E0601

  Continuous positive airway pressure (cpap) device

• E0602

  Breast pump, manual, any type

• E0603

  Breast pump, electric (ac and/or dc), any type

• E0604

  Breast pump, hospital grade, electric (ac and / or dc), any type

• E0605

  Vaporizer, room type

• E0606

  Postural drainage board

• E0607

  Home blood glucose monitor

• E0610

  Pacemaker monitor, self-contained, (checks battery depletion, includes audible and visible check systems)

• E0615

  Pacemaker monitor, self contained, checks battery depletion and other pacemaker components, includes digital/visible check systems

• E0616

  Implantable cardiac event recorder with memory, activator and programmer

• E0617

  External defibrillator with integrated electrocardiogram analysis

• E0618

  Apnea monitor, without recording feature

• E0619

  Apnea monitor, with recording feature

• E0620

  Skin piercing device for collection of capillary blood, laser, each

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HCPCS Level II codes and descriptors are approved and maintained jointly by the alpha-numeric editorial panel (consisting of CMS, the Health Insurance Association of America, and the Blue Cross and Blue Shield Association). — Updated 7/21/2026

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