Blue Cross/Blue Shield and other commercial payers develop S codes to report drugs, services, and supplies. These codes may not be used to bill services paid under any Medicare payment system. Medicare does not reimburse for services under S codes.

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• S9502

  Home infusion therapy, antibiotic, antiviral, or antifungal therapy; once every 8 hours, administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9503

  Home infusion therapy, antibiotic, antiviral, or antifungal; once every 6 hours; administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9504

  Home infusion therapy, antibiotic, antiviral, or antifungal; once every 4 hours; administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9529

  Routine venipuncture for collection of specimen(s), single home bound, nursing home, or skilled nursing facility patient

• S9537

  Home therapy; hematopoietic hormone injection therapy (e.g., erythropoietin, g-csf, gm-csf); administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9538

  Home transfusion of blood product(s); administrative services, professional pharmacy services, care coordination and all necessary supplies and equipment (blood products, drugs, and nursing visits coded separately), per diem

• S9542

  Home injectable therapy, not otherwise classified, including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9558

  Home injectable therapy; growth hormone, including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9559

  Home injectable therapy, interferon, including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9560

  Home injectable therapy; hormonal therapy (e.g.; leuprolide, goserelin), including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9562

  Home injectable therapy, palivizumab or other monoclonal antibody for rsv, including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9563

  Home injectable therapy, immunotherapy, including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9590

  Home therapy, irrigation therapy (e.g., sterile irrigation of an organ or anatomical cavity); including administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem

• S9810

  Home therapy; professional pharmacy services for provision of infusion, specialty drug administration, and/or disease state management, not otherwise classified, per hour (do not use this code with any per diem code)

• S9900

  Services by a journal-listed christian science practitioner for the purpose of healing, per diem

• S9901

  Services by a journal-listed christian science nurse, per hour

• S9960

  Ambulance service, conventional air service, nonemergency transport, one way (fixed wing)

• S9961

  Ambulance service, conventional air service, nonemergency transport, one way (rotary wing)

• S9970

  Health club membership, annual

• S9975

  Transplant related lodging, meals and transportation, per diem

• S9976

  Lodging, per diem, not otherwise classified

• S9977

  Meals, per diem, not otherwise specified

• S9981

  Medical records copying fee, administrative

• S9982

  Medical records copying fee, per page

• S9986

  Not medically necessary service (patient is aware that service not medically necessary)

• S9988

  Services provided as part of a phase i clinical trial

• S9989

  Services provided outside of the united states of america (list in addition to code(s) for service(s))

• S9990

  Services provided as part of a phase ii clinical trial

• S9991

  Services provided as part of a phase iii clinical trial

• S9992

  Transportation costs to and from trial location and local transportation costs (e.g., fares for taxicab or bus) for clinical trial participant and one caregiver/companion

• S9994

  Lodging costs (e.g., hotel charges) for clinical trial participant and one caregiver/companion

• S9996

  Meals for clinical trial participant and one caregiver/companion

• S9999

  Sales tax

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HCPCS Level II codes and descriptors are approved and maintained jointly by the alpha-numeric editorial panel (consisting of CMS, the Health Insurance Association of America, and the Blue Cross and Blue Shield Association). — Updated 6/4/2026

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