Blue Cross/Blue Shield and other commercial payers develop S codes to report drugs, services, and supplies. These codes may not be used to bill services paid under any Medicare payment system. Medicare does not reimburse for services under S codes.

View All HCPCS Sections

• S2409

  Repair, congenital malformation of fetus, procedure performed in utero, not otherwise classified

• S2411

  Fetoscopic laser therapy for treatment of twin-to-twin transfusion syndrome

• S2900

  Surgical techniques requiring use of robotic surgical system (list separately in addition to code for primary procedure)

• S3000

  Diabetic indicator; retinal eye exam, dilated, bilateral

• S3005

  Performance measurement, evaluation of patient self assessment, depression

• S3600

  Stat laboratory request (situations other than s3601)

• S3601

  Emergency stat laboratory charge for patient who is homebound or residing in a nursing facility

• S3620

  Newborn metabolic screening panel, includes test kit, postage and the laboratory tests specified by the state for inclusion in this panel (e.g., galactose; hemoglobin, electrophoresis; hydroxyprogesterone, 17-d; phenylalanine (pku); and thyroxine, total)

• S3630

  Eosinophil count, blood, direct

• S3645

  Hiv-1 antibody testing of oral mucosal transudate

• S3650

  Saliva test, hormone level; during menopause

• S3652

  Saliva test, hormone level; to assess preterm labor risk

• S3655

  Antisperm antibodies test (immunobead)

• S3708

  Gastrointestinal fat absorption study

• S3721

  Prostate cancer antigen 3 (pca3) testing

• S3722

  Dose optimization by area under the curve (auc) analysis, for infusional 5-fluorouracil

• S3800

  Genetic testing for amyotrophic lateral sclerosis (als)

• S3840

  Dna analysis for germline mutations of the ret proto-oncogene for susceptibility to multiple endocrine neoplasia type 2

• S3841

  Genetic testing for retinoblastoma

• S3842

  Genetic testing for von hippel-lindau disease

• S3844

  Dna analysis of the connexin 26 gene (gjb2) for susceptibility to congenital, profound deafness

• S3845

  Genetic testing for alpha-thalassemia

• S3846

  Genetic testing for hemoglobin e beta-thalassemia

• S3849

  Genetic testing for niemann-pick disease

• S3850

  Genetic testing for sickle cell anemia

• S3852

  Dna analysis for apoe epsilon 4 allele for susceptibility to alzheimer's disease

• S3853

  Genetic testing for myotonic muscular dystrophy

• S3854

  Gene expression profiling panel for use in the management of breast cancer treatment

• S3855

  Genetic testing for detection of mutations in the presenilin - 1 gene

• S3861

  Genetic testing, sodium channel, voltage-gated, type v, alpha subunit (scn5a) and variants for suspected brugada syndrome

• S3865

  Comprehensive gene sequence analysis for hypertrophic cardiomyopathy

• S3866

  Genetic analysis for a specific gene mutation for hypertrophic cardiomyopathy (hcm) in an individual with a known hcm mutation in the family

• S3870

  Comparative genomic hybridization (cgh) microarray testing for developmental delay, autism spectrum disorder and/or intellectual disability

• S3890

  Dna analysis, fecal, for colorectal cancer screening

• S3900

  Surface electromyography (emg)

• S3902

  Ballistocardiogram

• S3904

  Masters two step

• S4005

  Interim labor facility global (labor occurring but not resulting in delivery)

• S4011

  In vitro fertilization; including but not limited to identification and incubation of mature oocytes, fertilization with sperm, incubation of embryo(s), and subsequent visualization for determination of development

• S4013

  Complete cycle, gamete intrafallopian transfer (gift), case rate

• S4014

  Complete cycle, zygote intrafallopian transfer (zift), case rate

• S4015

  Complete in vitro fertilization cycle, not otherwise specified, case rate

• S4016

  Frozen in vitro fertilization cycle, case rate

• S4017

  Incomplete cycle, treatment cancelled prior to stimulation, case rate

• S4018

  Frozen embryo transfer procedure cancelled before transfer, case rate

• S4020

  In vitro fertilization procedure cancelled before aspiration, case rate

• S4021

  In vitro fertilization procedure cancelled after aspiration, case rate

• S4022

  Assisted oocyte fertilization, case rate

• S4023

  Donor egg cycle, incomplete, case rate

• S4024

  Air polymer-type a intrauterine foam, per study dose

---

HCPCS Level II codes and descriptors are approved and maintained jointly by the alpha-numeric editorial panel (consisting of CMS, the Health Insurance Association of America, and the Blue Cross and Blue Shield Association). — Updated 7/24/2026

CPT^® is a registered trademark of the American Medical Association (AMA). All rights reserved.